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Spilanthol from Acmella Oleracea Lowers the Intracellular Levels of cAMP Impairing NKCC2 Phosphorylation and Water Channel AQP2 Membrane Expression in Mouse Kidney

Acmella oleracea is well recognized in Brazilian traditional medicine as diuretic, although few scientific data have been published to support this effect. Aim of this study was to determine the molecular effect of Acmella oleracea extract and its main alkylamide spilanthol on two major processes in...

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Detalles Bibliográficos
Autores principales: Gerbino, Andrea, Schena, Giorgia, Milano, Serena, Milella, Luigi, Barbosa, Alan Franco, Armentano, Francesca, Procino, Giuseppe, Svelto, Maria, Carmosino, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877099/
https://www.ncbi.nlm.nih.gov/pubmed/27213818
http://dx.doi.org/10.1371/journal.pone.0156021