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Lovastatin Decreases the Expression of CD133 and Influences the Differentiation Potential of Human Embryonic Stem Cells

The lipophilic statin lovastatin decreases cholesterol synthesis and is a safe and effective treatment for the prevention of cardiovascular diseases. Growing evidence points at antitumor potential of lovastatin. Therefore, understanding the molecular mechanism of lovastatin function in different cel...

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Detalles Bibliográficos
Autores principales: Kallas-Kivi, Ade, Trei, Annika, Maimets, Toivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877483/
https://www.ncbi.nlm.nih.gov/pubmed/27247576
http://dx.doi.org/10.1155/2016/1580701