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A New Defective Helper RNA to Produce Recombinant Sindbis Virus that Infects Neurons but does not Propagate
Recombinant Sindbis viruses are important tools in neuroscience because they combine rapid and high transgene expression with a capacity to carry large transgenes. Currently, two packaging systems based on the defective helper (DH) RNAs DH(26S)5’SIN and DH-BB(tRNA;TE12) are available for generating...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877524/ https://www.ncbi.nlm.nih.gov/pubmed/27252627 http://dx.doi.org/10.3389/fnana.2016.00056 |