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Sildenafil Ameliorates Advanced Glycation End Products-Induced Mitochondrial Dysfunction in HT-22 Hippocampal Neuronal Cells

OBJECTIVE: Accumulation of advanced glycation end-products (AGE) and mitochondrial glycation is importantly implicated in the pathological changes of the brain associated with diabetic complications, Alzheimer disease, and aging. The present study was undertaken to determine whether sildenafil, a ty...

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Detalles Bibliográficos
Autores principales: Sung, Soon Ki, Woo, Jae Suk, Kim, Young Ha, Son, Dong Wuk, Lee, Sang Weon, Song, Geun Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Neurosurgical Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877549/
https://www.ncbi.nlm.nih.gov/pubmed/27226858
http://dx.doi.org/10.3340/jkns.2016.59.3.259