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Motile properties of the bi-directional kinesin-5 Cin8 are affected by phosphorylation in its motor domain

The Saccharomyces cerevisiae kinesin-5 Cin8 performs essential mitotic functions in spindle assembly and anaphase B spindle elongation. Recent work has shown that Cin8 is a bi-directional motor which moves towards the minus-end of microtubules (MTs) under high ionic strength (IS) conditions and chan...

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Detalles Bibliográficos
Autores principales: Shapira, Ofer, Gheber, Larisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877575/
https://www.ncbi.nlm.nih.gov/pubmed/27216310
http://dx.doi.org/10.1038/srep25597