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QSAR Accelerated Discovery of Potent Ice Recrystallization Inhibitors

Ice recrystallization is the main contributor to cell damage and death during the cryopreservation of cells and tissues. Over the past five years, many small carbohydrate-based molecules were identified as ice recrystallization inhibitors and several were shown to reduce cryoinjury during the cryopr...

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Detalles Bibliográficos
Autores principales: Briard, Jennie G., Fernandez, Michael, De Luna, Phil, Woo, Tom. K., Ben, Robert N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877635/
https://www.ncbi.nlm.nih.gov/pubmed/27216585
http://dx.doi.org/10.1038/srep26403