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Ectodomain Architecture Affects Sequence and Functional Evolution of Vertebrate Toll-like Receptors
Toll-like receptors (TLRs) are crucial components of innate immunity that specifically recognize diverse pathogen-associated molecular patterns from pathogens. The continuous hydrogen-bond network (asparagine ladder) formed among the asparagine residues on the concave surfaces of neighboring leucine...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877655/ https://www.ncbi.nlm.nih.gov/pubmed/27216145 http://dx.doi.org/10.1038/srep26705 |