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Ectodomain Architecture Affects Sequence and Functional Evolution of Vertebrate Toll-like Receptors

Toll-like receptors (TLRs) are crucial components of innate immunity that specifically recognize diverse pathogen-associated molecular patterns from pathogens. The continuous hydrogen-bond network (asparagine ladder) formed among the asparagine residues on the concave surfaces of neighboring leucine...

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Detalles Bibliográficos
Autores principales:	Wang, Jinlan, Zhang, Zheng, Liu, Jing, Zhao, Jing, Yin, Deling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877655/ https://www.ncbi.nlm.nih.gov/pubmed/27216145 http://dx.doi.org/10.1038/srep26705

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