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Raptor/mTORC1 loss in adipocytes causes progressive lipodystrophy and fatty liver disease
OBJECTIVE: Normal adipose tissue growth and function is critical to maintaining metabolic homeostasis and its excess (e.g. obesity) or absence (e.g. lipodystrophy) is associated with severe metabolic disease. The goal of this study was to understand the mechanisms maintaining healthy adipose tissue...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877665/ https://www.ncbi.nlm.nih.gov/pubmed/27257602 http://dx.doi.org/10.1016/j.molmet.2016.04.001 |