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SLICER: inferring branched, nonlinear cellular trajectories from single cell RNA-seq data
Single cell experiments provide an unprecedented opportunity to reconstruct a sequence of changes in a biological process from individual “snapshots” of cells. However, nonlinear gene expression changes, genes unrelated to the process, and the possibility of branching trajectories make this a challe...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877799/ https://www.ncbi.nlm.nih.gov/pubmed/27215581 http://dx.doi.org/10.1186/s13059-016-0975-3 |