Identification, characterization and molecular adaptation of class I redox systems for the production of hydroxylated diterpenoids

BACKGROUND: De novo production of multi-hydroxylated diterpenoids is challenging due to the lack of efficient redox systems. RESULTS: In this study a new reductase/ferredoxin system from Streptomyces afghaniensis (AfR·Afx) was identified, which allowed the Escherichia coli-based production of the tr...

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Detalles Bibliográficos
Autores principales: Görner, Christian, Schrepfer, Patrick, Redai, Veronika, Wallrapp, Frank, Loll, Bernhard, Eisenreich, Wolfgang, Haslbeck, Martin, Brück, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877809/
https://www.ncbi.nlm.nih.gov/pubmed/27216162
http://dx.doi.org/10.1186/s12934-016-0487-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877809/
https://www.ncbi.nlm.nih.gov/pubmed/27216162
http://dx.doi.org/10.1186/s12934-016-0487-6

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