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Detection of BCR/ABL Translocation in Bone Marrow Derived Mesenchymal Stem Cells in Egyptian CML Patients

BACKGROUND: Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder of hematopoietic stem cells. It is characterized at the cytogenetic level by Philadelphia (ph) chromosome and at the molecular level by the BCR/ABL gene rearrangement. Bone marrow derived mesenchymal stem cells (MSCs)...

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Detalles Bibliográficos
Autores principales: Gaafar, Taghrid Mohamed, Raafat, Inas Ismail, Aly, Azza Ahmed, Mohamed, Nagwa Abd EL-Ghaffar, Farid, Reem Jan, Saad, Neveen Ezzat, EL-Hawary, Rabab, Mostafaa, Naglaa, Ahmed, Mirhan Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Institute of Immunobiology and Human Genetics 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877858/
https://www.ncbi.nlm.nih.gov/pubmed/27275226
http://dx.doi.org/10.3889/oamjms.2015.040