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Comparison of next generation sequencing, SNaPshot assay and real-time polymerase chain reaction for lung adenocarcinoma EGFR mutation assessment

BACKGROUND: The epidermal growth factor receptor (EGFR) mutation status assessment has become increasingly important given the significant impact of tyrosine kinase inhibitors in lung cancer management. Our aim was to compare real life operational characteristics for three EGFR mutation assays - two...

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Detalles Bibliográficos
Autores principales: Cernomaz, Andrei-Tudor, Macovei, Ina Iuliana, Pavel, Ionut, Grigoriu, Carmen, Marinca, Mihai, Baty, Florent, Peter, Simona, Zonda, Radu, Brutsche, Martin, Grigoriu, Bogdan- Dragos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877937/
https://www.ncbi.nlm.nih.gov/pubmed/27215400
http://dx.doi.org/10.1186/s12890-016-0250-0