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Environment-driven somatic mosaicism in brain disorders

The identification of somatic mosaicism in the brain lends a new perspective to our understanding of the role of gene and environment interactions in psychiatric disease risk. Somatic mutations, such as retrotransposon insertions, that are precipitated by modern environmental factors may alter neuro...

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Detalles Bibliográficos
Autores principales: Bedrosian, Tracy A., Linker, Sara, Gage, Fred H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877941/
https://www.ncbi.nlm.nih.gov/pubmed/27215330
http://dx.doi.org/10.1186/s13073-016-0317-9