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Disagreement between two common biomarkers of global DNA methylation

BACKGROUND: The quantification of global DNA methylation has been established in epigenetic screening. As more practicable alternatives to the HPLC-based gold standard, the methylation analysis of CpG islands in repeatable elements (LINE-1) and the luminometric methylation assay (LUMA) of overall 5-...

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Detalles Bibliográficos
Autores principales: Knothe, Claudia, Shiratori, Hiromi, Resch, Eduard, Ultsch, Alfred, Geisslinger, Gerd, Doehring, Alexandra, Lötsch, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877994/
https://www.ncbi.nlm.nih.gov/pubmed/27222668
http://dx.doi.org/10.1186/s13148-016-0227-0