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Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway
BACKGROUND: Excessive autophagy induced by extravagant oxidative stress is the main reason for diabetes-induced vascular endothelial cells dysfunction. Hydrogen sulfide (H(2)S) has anti-oxidative effects but its regulation on excessive autophagy of vascular endothelial cells is unclear. METHODS: In...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877995/ https://www.ncbi.nlm.nih.gov/pubmed/27222705 http://dx.doi.org/10.1186/s13578-016-0099-1 |