Cargando…

Mapping the landscape of metabolic goals of a cell

Genome-scale flux balance models of metabolism provide testable predictions of all metabolic rates in an organism, by assuming that the cell is optimizing a metabolic goal known as the objective function. We introduce an efficient inverse flux balance analysis (invFBA) approach, based on linear prog...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Qi, Stettner, Arion I., Reznik, Ed, Paschalidis, Ioannis Ch., Segrè, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878026/
https://www.ncbi.nlm.nih.gov/pubmed/27215445
http://dx.doi.org/10.1186/s13059-016-0968-2