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Enhancing antibody folding and secretion by tailoring the Saccharomyces cerevisiae endoplasmic reticulum

BACKGROUND: The yeast Saccharomyces cerevisiae provides intriguing possibilities for synthetic biology and bioprocess applications, but its use is still constrained by cellular characteristics that limit the product yields. Considering the production of advanced biopharmaceuticals, a major hindrance...

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Detalles Bibliográficos
Autores principales: de Ruijter, Jorg C., Koskela, Essi V., Frey, Alexander D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878073/
https://www.ncbi.nlm.nih.gov/pubmed/27216259
http://dx.doi.org/10.1186/s12934-016-0488-5