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Enhancing antibody folding and secretion by tailoring the Saccharomyces cerevisiae endoplasmic reticulum
BACKGROUND: The yeast Saccharomyces cerevisiae provides intriguing possibilities for synthetic biology and bioprocess applications, but its use is still constrained by cellular characteristics that limit the product yields. Considering the production of advanced biopharmaceuticals, a major hindrance...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878073/ https://www.ncbi.nlm.nih.gov/pubmed/27216259 http://dx.doi.org/10.1186/s12934-016-0488-5 |