The emerging role of viral vectors as vehicles for DMD gene editing

Duchenne muscular dystrophy (DMD) is a genetic disorder caused by mutations in the dystrophin-encoding DMD gene. The DMD gene, spanning over 2.4 megabases along the short arm of the X chromosome (Xp21.2), is the largest genetic locus known in the human genome. The size of DMD, combined with the comp...

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Detalles Bibliográficos
Autores principales: Maggio, Ignazio, Chen, Xiaoyu, Gonçalves, Manuel A. F. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878080/
https://www.ncbi.nlm.nih.gov/pubmed/27215286
http://dx.doi.org/10.1186/s13073-016-0316-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878080/
https://www.ncbi.nlm.nih.gov/pubmed/27215286
http://dx.doi.org/10.1186/s13073-016-0316-x

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