Aberrant Alternative Polyadenylation is Responsible for Survivin Up-regulation in Ovarian Cancer

BACKGROUND: Survivin is an oncoprotein silenced in normal mature tissues but reactivated in serous ovarian cancer (SOC). Although transcriptional activation is assumed for its overexpression, the long 3'-untranslated region (3'-UTR) in survivin gene, which contains many alternate polyadeny...

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Detalles Bibliográficos
Autores principales: He, Xiang-Jun, Zhang, Qi, Ma, Li-Ping, Li, Na, Chang, Xiao-Hong, Zhang, Yu-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878157/
https://www.ncbi.nlm.nih.gov/pubmed/27174320
http://dx.doi.org/10.4103/0366-6999.181965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878157/
https://www.ncbi.nlm.nih.gov/pubmed/27174320
http://dx.doi.org/10.4103/0366-6999.181965

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