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Aberrant Alternative Polyadenylation is Responsible for Survivin Up-regulation in Ovarian Cancer
BACKGROUND: Survivin is an oncoprotein silenced in normal mature tissues but reactivated in serous ovarian cancer (SOC). Although transcriptional activation is assumed for its overexpression, the long 3'-untranslated region (3'-UTR) in survivin gene, which contains many alternate polyadeny...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878157/ https://www.ncbi.nlm.nih.gov/pubmed/27174320 http://dx.doi.org/10.4103/0366-6999.181965 |