Exocytosis of macrophage lysosomes leads to digestion of apoptotic adipocytes and foam cell formation

Many types of apoptotic cells are phagocytosed and digested by macrophages. Adipocytes can be hundreds of times larger than macrophages, so they are too large to be digested by conventional phagocytic processes. The nature of the interaction between macrophages and apoptotic adipocytes has not been...

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Detalles Bibliográficos
Autores principales: Haka, Abigail S., Barbosa-Lorenzi, Valéria C., Lee, Hyuek Jong, Falcone, Domenick J., Hudis, Clifford A., Dannenberg, Andrew J., Maxfield, Frederick R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878183/
https://www.ncbi.nlm.nih.gov/pubmed/27044658
http://dx.doi.org/10.1194/jlr.M064089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878183/
https://www.ncbi.nlm.nih.gov/pubmed/27044658
http://dx.doi.org/10.1194/jlr.M064089

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