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Exocytosis of macrophage lysosomes leads to digestion of apoptotic adipocytes and foam cell formation
Many types of apoptotic cells are phagocytosed and digested by macrophages. Adipocytes can be hundreds of times larger than macrophages, so they are too large to be digested by conventional phagocytic processes. The nature of the interaction between macrophages and apoptotic adipocytes has not been...
Autores principales: | Haka, Abigail S., Barbosa-Lorenzi, Valéria C., Lee, Hyuek Jong, Falcone, Domenick J., Hudis, Clifford A., Dannenberg, Andrew J., Maxfield, Frederick R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878183/ https://www.ncbi.nlm.nih.gov/pubmed/27044658 http://dx.doi.org/10.1194/jlr.M064089 |
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