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Thrombin stimulates insulin secretion via protease-activated receptor-3

The disease mechanisms underlying type 2 diabetes (T2D) remain poorly defined. Here we aimed to explore the pathophysiology of T2D by analyzing gene co-expression networks in human islets. Using partial correlation networks we identified a group of co-expressed genes (‘module’) including F2RL2 that...

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Detalles Bibliográficos
Autores principales: Hänzelmann, Sonja, Wang, Jinling, Güney, Emre, Tang, Yunzhao, Zhang, Enming, Axelsson, Annika S, Nenonen, Hannah, Salehi, Albert S, Wollheim, Claes B, Zetterberg, Eva, Berntorp, Erik, Costa, Ivan G, Castelo, Robert, Rosengren, Anders H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878264/
https://www.ncbi.nlm.nih.gov/pubmed/26742564
http://dx.doi.org/10.1080/19382014.2015.1118195