Autophagy deficiency in β cells blunts incretin-induced suppression of glucagon release from α cells

Incretin-based therapy such as GLP-1 receptor agonists and DPP-4 inhibitors for type 2 diabetes mellitus is characterized by glucose-dependent insulin secretion and glucose-inhibited glucagon secretion. Recently, autophagy deficiency in islet β cells has been shown to contribute to the pathogenesis...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Min Joo, Choi, Ok Kyong, Chae, Kyung Sil, Lee, Hakmo, Chung, Sung Soo, Ham, Dong-Sik, Kim, Ji-Won, Yoon, Kun-Ho, Park, Kyong Soo, Jung, Hye Seung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878271/
https://www.ncbi.nlm.nih.gov/pubmed/26744903
http://dx.doi.org/10.1080/19382014.2015.1129096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878271/
https://www.ncbi.nlm.nih.gov/pubmed/26744903
http://dx.doi.org/10.1080/19382014.2015.1129096

Ejemplares similares