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Development of Immunoassays for the Quantitative Assessment of Amyloid-β in the Presence of Therapeutic Antibody: Application to Pre-Clinical Studies

Utilizing decision making biomarkers in drug development requires thorough assay validation. Special considerations need to be taken into account when monitoring biomarkers using immunoassays in the presence of therapeutic antibodies. We have developed robust and sensitive assays to assess target en...

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Detalles Bibliográficos
Autores principales: Bogstedt, Anna, Groves, Maria, Tan, Keith, Narwal, Rajesh, McFarlane, Mary, Höglund, Kina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878309/
https://www.ncbi.nlm.nih.gov/pubmed/26402635
http://dx.doi.org/10.3233/JAD-142988