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The GLP-1 Receptor Agonist Liraglutide Improves Memory Function and Increases Hippocampal CA1 Neuronal Numbers in a Senescence-Accelerated Mouse Model of Alzheimer’s Disease

Recent studies indicate that glucagon-like peptide 1 (GLP-1) receptor agonists, currently used in the management of type 2 diabetes, exhibit neurotrophic and neuroprotective effects in amyloid-β (Aβ) toxicity models of Alzheimer’s disease (AD). We investigated the potential pro-cognitive and neuropr...

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Detalles Bibliográficos
Autores principales: Hansen, Henrik H., Fabricius, Katrine, Barkholt, Pernille, Niehoff, Michael L., Morley, John E., Jelsing, Jacob, Pyke, Charles, Knudsen, Lotte Bjerre, Farr, Susan A., Vrang, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878312/
https://www.ncbi.nlm.nih.gov/pubmed/25869785
http://dx.doi.org/10.3233/JAD-143090