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Assessing Metabolic Changes in Response to mTOR Inhibition in a Mantle Cell Lymphoma Xenograft Model Using AcidoCEST MRI

AcidoCEST magnetic resonance imaging (MRI) has previously been shown to measure tumor extracellular pH (pHe) with excellent accuracy and precision. This study investigated the ability of acidoCEST MRI to monitor changes in tumor pHe in response to therapy. To perform this study, we used the Granta 5...

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Detalles Bibliográficos
Autores principales: Akhenblit, Paul J., Hanke, Neale T., Gill, Alexander, Persky, Daniel O., Howison, Christine M., Pagel, Mark D., Baker, Amanda F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878391/
https://www.ncbi.nlm.nih.gov/pubmed/27140422
http://dx.doi.org/10.1177/1536012116645439