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Assessing Metabolic Changes in Response to mTOR Inhibition in a Mantle Cell Lymphoma Xenograft Model Using AcidoCEST MRI
AcidoCEST magnetic resonance imaging (MRI) has previously been shown to measure tumor extracellular pH (pHe) with excellent accuracy and precision. This study investigated the ability of acidoCEST MRI to monitor changes in tumor pHe in response to therapy. To perform this study, we used the Granta 5...
Autores principales: | Akhenblit, Paul J., Hanke, Neale T., Gill, Alexander, Persky, Daniel O., Howison, Christine M., Pagel, Mark D., Baker, Amanda F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878391/ https://www.ncbi.nlm.nih.gov/pubmed/27140422 http://dx.doi.org/10.1177/1536012116645439 |
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