Cargando…

Myeloid Deletion of α1AMPK Exacerbates Atherosclerosis in LDL Receptor Knockout (LDLRKO) Mice

Macrophage inflammation marks all stages of atherogenesis, and AMPK is a regulator of macrophage inflammation. We therefore generated myeloid α1AMPK knockout (MAKO) mice on the LDL receptor knockout (LDLRKO) background to investigate whether myeloid deletion of α1AMPK exacerbates atherosclerosis. Wh...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Qiang, Cui, Xin, Wu, Rui, Zha, Lin, Wang, Xianfeng, Parks, John S., Yu, Liqing, Shi, Hang, Xue, Bingzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878417/
https://www.ncbi.nlm.nih.gov/pubmed/26822081
http://dx.doi.org/10.2337/db15-0917