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Simvastatin ameliorates ventricular remodeling via the TGF-β1 signaling pathway in rats following myocardial infarction

Statins are widely used in patients with cardiovascular diseases. A considerable number of previous studies revealed that the intracellular signaling of transforming growth factor (TGF)-β1 mediated the development of cardiomyocyte hypertrophy and interstitial fibrosis. However, whether statins can a...

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Detalles Bibliográficos
Autores principales: XIAO, XIANGBIN, CHANG, GUANGLEI, LIU, JIAN, SUN, GUANGYUN, LIU, LI, QIN, SHU, ZHANG, DONGYING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878547/
https://www.ncbi.nlm.nih.gov/pubmed/27121011
http://dx.doi.org/10.3892/mmr.2016.5178