Cannabinoid WIN-55,212-2 mesylate inhibits ADAMTS-4 activity in human osteoarthritic articular chondrocytes by inhibiting expression of syndecan-1

A central feature of osteoarthritis (OA) is the loss of articular cartilage, which is primarily attributed to cartilage breakdown. A group of metalloproteinases termed the A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) family are reported to be important in cartilage breakdo...

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Detalles Bibliográficos
Autores principales: KONG, YING, WANG, WANCHUN, ZHANG, CHANGJIE, WU, YI, LIU, YANG, ZHOU, XIAORONG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878569/
https://www.ncbi.nlm.nih.gov/pubmed/27082728
http://dx.doi.org/10.3892/mmr.2016.5137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878569/
https://www.ncbi.nlm.nih.gov/pubmed/27082728
http://dx.doi.org/10.3892/mmr.2016.5137

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