Cargando…

CFIm25 regulates glutaminase alternative terminal exon definition to modulate miR-23 function

Alternative polyadenylation (APA) and alternative splicing (AS) provide mRNAs with the means to avoid microRNA repression through selective shortening or differential usage of 3′UTRs. The two glutaminase (GLS) mRNA isoforms, termed KGA and GAC, contain distinct 3′UTRs with the KGA isoform subject to...

Descripción completa

Detalles Bibliográficos
Autores principales: Masamha, Chioniso P., Xia, Zheng, Peart, Natoya, Collum, Scott, Li, Wei, Wagner, Eric J., Shyu, Ann-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878610/
https://www.ncbi.nlm.nih.gov/pubmed/27095025
http://dx.doi.org/10.1261/rna.055939.116