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Packaging of Mason-Pfizer monkey virus (MPMV) genomic RNA depends upon conserved long-range interactions (LRIs) between U5 and gag sequences

MPMV has great potential for development as a vector for gene therapy. In this respect, precisely defining the sequences and structural motifs that are important for dimerization and packaging of its genomic RNA (gRNA) are of utmost importance. A distinguishing feature of the MPMV gRNA packaging sig...

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Detalles Bibliográficos
Autores principales: Kalloush, Rawan M., Vivet-Boudou, Valérie, Ali, Lizna M., Mustafa, Farah, Marquet, Roland, Rizvi, Tahir A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878616/
https://www.ncbi.nlm.nih.gov/pubmed/27095024
http://dx.doi.org/10.1261/rna.055731.115