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Using in-cell SHAPE-Seq and simulations to probe structure–function design principles of RNA transcriptional regulators

Antisense RNA-mediated transcriptional regulators are powerful tools for controlling gene expression and creating synthetic gene networks. RNA transcriptional repressors derived from natural mechanisms called attenuators are particularly versatile, though their mechanistic complexity has made them d...

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Detalles Bibliográficos
Autores principales: Takahashi, Melissa K., Watters, Kyle E., Gasper, Paul M., Abbott, Timothy R., Carlson, Paul D., Chen, Alan A., Lucks, Julius B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878617/
https://www.ncbi.nlm.nih.gov/pubmed/27103533
http://dx.doi.org/10.1261/rna.054916.115