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Sensitization by subcutaneous route is superior to intraperitoneal route in induction of asthma by house dust mite in a murine mode

OBJECTIVE: To develop a new experimental model of chronic allergic pulmonary disease induced by house dust mite, with marked production of specific immunoglobulin E (IgE), eosinophilic inflammatory infiltrate in the airways and remodeling, comparing two different routes of sensitization. METHODS: Th...

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Detalles Bibliográficos
Autores principales: Aun, Marcelo Vivolo, Saraiva-Romanholo, Beatriz Mangueira, de Almeida, Francine Maria, Brüggemann, Thayse Regina, Kalil, Jorge, Martins, Milton de Arruda, Arantes-Costa, Fernanda Magalhães, Giavina-Bianchi, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878631/
https://www.ncbi.nlm.nih.gov/pubmed/26761554
http://dx.doi.org/10.1590/S1679-45082015AO3389