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Ani9, A Novel Potent Small-Molecule ANO1 Inhibitor with Negligible Effect on ANO2

Anoctamin1 (ANO1)/transmembrane protein 16A (TMEM16A), a calcium-activated chloride channel (CaCC), is involved in many physiological functions such as fluid secretion, smooth muscle contraction, nociception and cancer progression. To date, only a few ANO1 inhibitors have been described, and these h...

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Detalles Bibliográficos
Autores principales: Seo, Yohan, Lee, Ho K., Park, Jinhong, Jeon, Dong-kyu, Jo, Sungwoo, Jo, Minjae, Namkung, Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878759/
https://www.ncbi.nlm.nih.gov/pubmed/27219012
http://dx.doi.org/10.1371/journal.pone.0155771