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Ani9, A Novel Potent Small-Molecule ANO1 Inhibitor with Negligible Effect on ANO2
Anoctamin1 (ANO1)/transmembrane protein 16A (TMEM16A), a calcium-activated chloride channel (CaCC), is involved in many physiological functions such as fluid secretion, smooth muscle contraction, nociception and cancer progression. To date, only a few ANO1 inhibitors have been described, and these h...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878759/ https://www.ncbi.nlm.nih.gov/pubmed/27219012 http://dx.doi.org/10.1371/journal.pone.0155771 |