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Computational Framework for Prediction of Peptide Sequences That May Mediate Multiple Protein Interactions in Cancer-Associated Hub Proteins

A considerable proportion of protein-protein interactions (PPIs) in the cell are estimated to be mediated by very short peptide segments that approximately conform to specific sequence patterns known as linear motifs (LMs), often present in the disordered regions in the eukaryotic proteins. These pe...

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Detalles Bibliográficos
Autores principales: Sarkar, Debasree, Patra, Piya, Ghosh, Abhirupa, Saha, Sudipto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878775/
https://www.ncbi.nlm.nih.gov/pubmed/27218803
http://dx.doi.org/10.1371/journal.pone.0155911