Epothilones Suppress Neointimal Thickening in the Rat Carotid Balloon-Injury Model by Inducing Vascular Smooth Muscle Cell Apoptosis through p53-Dependent Signaling Pathway

Microtubule stabilizing agents (MTSA) are known to inhibit vascular smooth muscle cell (VSMC) proliferation and migration, and effectively reduce neointimal hyperplasia and restenosis. Epothilones (EPOs), non-taxane MTSA, have been found to be effective in the inhibition of VSMC proliferation and ne...

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Detalles Bibliográficos
Autores principales: Son, Dong Ju, Jung, Jae Chul, Hong, Jin Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878802/
https://www.ncbi.nlm.nih.gov/pubmed/27218463
http://dx.doi.org/10.1371/journal.pone.0155859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878802/
https://www.ncbi.nlm.nih.gov/pubmed/27218463
http://dx.doi.org/10.1371/journal.pone.0155859

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