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A FRET-based study reveals site-specific regulation of spindle position checkpoint proteins at yeast centrosomes

The spindle position checkpoint (SPOC) is a spindle pole body (SPB, equivalent of mammalian centrosome) associated surveillance mechanism that halts mitotic exit upon spindle mis-orientation. Here, we monitored the interaction between SPB proteins and the SPOC component Bfa1 by FRET microscopy. We s...

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Detalles Bibliográficos
Autores principales: Gryaznova, Yuliya, Caydasi, Ayse Koca, Malengo, Gabriele, Sourjik, Victor, Pereira, Gislene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878874/
https://www.ncbi.nlm.nih.gov/pubmed/27159239
http://dx.doi.org/10.7554/eLife.14029