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Sex differences in cerebellar synaptic transmission and sex-specific responses to autism-linked Gabrb3 mutations in mice

Neurons of the cerebellar nuclei (CbN) transmit cerebellar signals to premotor areas. The cerebellum expresses several autism-linked genes, including GABRB3, which encodes GABA(A) receptor β3 subunits and is among the maternal alleles deleted in Angelman syndrome. We tested how this Gabrb3 m-/p+ mut...

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Detalles Bibliográficos
Autores principales: Mercer, Audrey A, Palarz, Kristin J, Tabatadze, Nino, Woolley, Catherine S, Raman, Indira M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878876/
https://www.ncbi.nlm.nih.gov/pubmed/27077953
http://dx.doi.org/10.7554/eLife.07596