Nasal Vaccination Stimulates CD8(+) T Cells for Potent Protection Against Mucosal Brucella melitensis Challenge

Brucellosis remains a significant zoonotic threat worldwide. Humans and animals acquire infection via their oropharynx and upper respiratory tract following oral or aerosol exposure. After mucosal infection, brucellosis develops into a systemic disease. Mucosal vaccination could offer a viable alter...

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Detalles Bibliográficos
Autores principales: Clapp, Beata, Yang, Xinghong, Thornburg, Theresa, Walters, Nancy, Pascual, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879022/
https://www.ncbi.nlm.nih.gov/pubmed/26752510
http://dx.doi.org/10.1038/icb.2016.5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879022/
https://www.ncbi.nlm.nih.gov/pubmed/26752510
http://dx.doi.org/10.1038/icb.2016.5

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