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Nasal Vaccination Stimulates CD8(+) T Cells for Potent Protection Against Mucosal Brucella melitensis Challenge
Brucellosis remains a significant zoonotic threat worldwide. Humans and animals acquire infection via their oropharynx and upper respiratory tract following oral or aerosol exposure. After mucosal infection, brucellosis develops into a systemic disease. Mucosal vaccination could offer a viable alter...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879022/ https://www.ncbi.nlm.nih.gov/pubmed/26752510 http://dx.doi.org/10.1038/icb.2016.5 |