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Accessory Factors of Cytoplasmic Viral RNA Sensors Required for Antiviral Innate Immune Response
Type I interferon (IFN) induces many antiviral factors in host cells. RIG-I-like receptors (RLRs) are cytoplasmic viral RNA sensors that trigger the signal to induce the innate immune response that includes type I IFN production. RIG-I and MDA5 are RLRs that form nucleoprotein filaments along viral...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879126/ https://www.ncbi.nlm.nih.gov/pubmed/27252702 http://dx.doi.org/10.3389/fimmu.2016.00200 |