Inhibition of Lysine-Specific Demethylase-1 (LSD1/KDM1A) Promotes the Adipogenic Differentiation of hESCs Through H3K4 Methylation

Given their totipotency, human embryonic stem cells (hESCs) can differentiate into all types of cells, including adipocytes, and provide an excellent research model for studying diseases associated with the metabolism of adipocytes, such as obesity and diabetes mellitus. Epigenetic regulation, inclu...

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Detalles Bibliográficos
Autores principales: Xiong, Yujing, Wang, Enyin, Huang, Yan, Guo, Xiaoyi, Yu, Yiping, Du, Qingyun, Ding, Xiaoyan, Sun, Yingpu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879152/
https://www.ncbi.nlm.nih.gov/pubmed/27059868
http://dx.doi.org/10.1007/s12015-016-9650-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879152/
https://www.ncbi.nlm.nih.gov/pubmed/27059868
http://dx.doi.org/10.1007/s12015-016-9650-z

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