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Inhibition of Lysine-Specific Demethylase-1 (LSD1/KDM1A) Promotes the Adipogenic Differentiation of hESCs Through H3K4 Methylation
Given their totipotency, human embryonic stem cells (hESCs) can differentiate into all types of cells, including adipocytes, and provide an excellent research model for studying diseases associated with the metabolism of adipocytes, such as obesity and diabetes mellitus. Epigenetic regulation, inclu...
Autores principales: | Xiong, Yujing, Wang, Enyin, Huang, Yan, Guo, Xiaoyi, Yu, Yiping, Du, Qingyun, Ding, Xiaoyan, Sun, Yingpu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879152/ https://www.ncbi.nlm.nih.gov/pubmed/27059868 http://dx.doi.org/10.1007/s12015-016-9650-z |
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