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Novel Approach for Clinical Validation of the cobas KRAS Mutation Test in Advanced Colorectal Cancer

AIM: Our objective was to assess the performance of the cobas test versus comparators for KRAS mutation status and predicting clinical response to anti-epidermal growth factor receptor (EGFR) therapy in patients with metastatic colorectal cancer (mCRC). METHODS: mCRC samples from 398 patients from R...

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Detalles Bibliográficos
Autores principales: Sharma, Abha, Zhang, Guili, Aslam, Shagufta, Yu, Karen, Chee, Melody, Palma, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879158/
https://www.ncbi.nlm.nih.gov/pubmed/26984642
http://dx.doi.org/10.1007/s40291-016-0193-4