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Short-lived mammals (shrew, mouse) have a less robust metal-responsive transcription factor than humans and bats

Non-essential “heavy” metals such as cadmium tend to accumulate in an organism and thus are a particular threat for long-lived animals. Here we show that two unrelated, short-lived groups of mammals (rodents and shrews, separated by 100 Mio years of evolution) each have independently acquired mutati...

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Detalles Bibliográficos
Autores principales: Schmidt, Katharina, Steiner, Kurt, Petrov, Boyan, Georgiev, Oleg, Schaffner, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879176/
https://www.ncbi.nlm.nih.gov/pubmed/27067444
http://dx.doi.org/10.1007/s10534-016-9926-4